This uses a combination of container and charade techniques - one word goes inside another, then combines with a third element to build the answer.
Look for a word meaning 'male' that goes inside a word meaning 'home'. Then add a word for 'troublemaker' - specifically a figure from Greek mythology known for mischief.
Answer: INMATE | M (male) goes inside IN (home) to give INM, then add ATE (Greek goddess of mischief and troublemaker) = INMATE